Clinical Topics

VA Research Offers Reassurance on Safety of TKIs for Kidney Cancer

VA Research Offers Reassurance on Safety of TKIs for Kidney Cancer

The U.S. Food and Drug Administration approval of several tyrosine kinase inhibitors (TKIs) over the last decade has substantially improved outcomes for patients with metastatic renal cell carcinoma.

California Statistics Indicate Kidney Cancer Rates Might Be Declining Overall

California Statistics Indicate Kidney Cancer Rates Might Be Declining Overall

After years of apparently rising rates of kidney cancer, the incidence of early-stage disease seems to be declining, at least in California.

Social Support Critical for Military Mental Health

The Marine Resiliency Study-II examined changes in symptomatology across a deployment cycle to Afghanistan. Results were published recently in the Journal of Psychiatric Research.1

Augmentation Better Than Switching Drugs in MDD

Augmentation Better Than Switching Drugs in MDD

The addition of an atypical anti-psychotic medication to an antidepressant regimen for veterans not responding to their current treatment led to greater improvement in symptoms of depression than switching to another antidepressant altogether.

Biomarkers Different in Acute HF Patients With, Without Diabetes

How diabetes affects pathophysiological processes among patients with acute heart failure (AHF) is unclear, according to a new study published in the European Journal of Heart Failure.1

Cleveland VA Pharmacy Clinic Shows Promise in Heart Failure Pilot

A pilot evaluation of a pharmacist-led, multidisciplinary transitional care clinic for heart failure (HF) patients showed good results at the Louis Stokes Cleveland VAMC in Cleveland.

Device Developers ‘Kicked a Hornet’s Nest’ in Hemorrhage and Shock Treatment

Device Developers ‘Kicked a Hornet’s Nest’ in Hemorrhage and Shock Treatment

For Air Force Col. Todd Rasmussen, MD, and Jonathan Eliason, MD, the idea for a new way to treat internal hemorrhaging on the battlefield was hard-won.

How Effective Are Implantable Cardioverter Defibrillators in Heart Failure?

It is not clear whether implantable cardioverter defibrillator (ICD) therapy improves survival

INVESTED Trial Tests High-Dose Flu Vaccine for Veterans With Cardiovascular Disease

INVESTED Trial Tests High-Dose Flu Vaccine for Veterans With Cardiovascular Disease

Influenza hits veterans hard, and older veterans with cardiovascular disease face a substantially increased risk of complications and death from the common ailment.

Severe Side Effects Rare in Elderly Veterans Receiving High Dose Influenza Vaccine

Severe Side Effects Rare in Elderly Veterans Receiving High Dose Influenza Vaccine

Patients over the age of 65 face an increased risk of severe complications and death if they contract influenza.

Study Suggests Physician Awareness of Natalizumab Side Effects

After a 43-year-old female with multiple sclerosis developed urethral melanoma, with the only potential risk factor being treatment with natalizumab

Home Exercise Helped Maintain Gait in Veterans With MS

BALTIMORE—Although physical rehabilitation is one of the few nonpharmaceutical therapies for maintaining or improving walking ability for patients with multiple sclerosis, many patients aren’t able to benefit because of travel distance to rehabilitation clinics, neurological disability and limited insurance coverage.… Read More

Lipoic Acid Promising in VA-Funded MS Study

PORTLAND, OR—While not many treatment options exist for patients with secondary progressive multiple sclerosis, a new study is suggesting that an over-the-counter remedy might improve quality of life. Research published in the journal Neuroimmunology & Neuroinflammation noted that the antioxidant… Read More

Factors Affecting Biochemical Recurrence of Prostate Cancer

DURHAM, NC—What is the association between lowest prostate-specific antigen (PSA) and time to nadir with biochemical recurrence (BCR) risk after radical prostatectomy (RP)? A study published recently in the journal Urology used the SEARCH database to try to answer that… Read More

Visceral Metastases Predict Overall PC Survival in Veterans

DURHAM, NC—Visceral metastases (VMs) are generally believed to predict worse prognoses compared with bone and lymph metastases in men with metastatic castration-resistant prostate cancer (mCRPC). Still, a new study published in the journal European Urology Focus pointed out that not… Read More

Veterans With PTSD Fare Worse With Concurrent Prostate Cancer

EAST NORTHPORT, NY—Being diagnosed with prostate cancer can be difficult enough. But what happens when the patient also is a veteran with post-traumatic stress disorder (PTSD)? A presentation at the 2017 American Society of Clinical Oncology explored that question.1 A… Read More

Suicide Attempts in Army Units Appear to Be 'Contagious'

Suicide Attempts in Army Units Appear to Be ‘Contagious’

Study Finds Links Between Higher Individual, Unit Rates BETHESDA, MD—Are soldiers in specific Army units more likely to attempt suicide? A new study looks at that issue and explores what characteristics of the units might influence the decision to take… Read More

Biomarkers Different in Acute HF Patients With, Without Diabetes

GRONINGEN, THE NETHERLANDS – How diabetes affects pathophysiological processes among patients with acute heart failure (AHF) is unclear, according to a new study published in the European Journal of Heart Failure.1 To add to that information, a study team led by the… Read More

Cleveland VA Pharmacy Clinic Shows Promise in Heart Failure Pilot

CLEVELAND – A pilot evaluation of a pharmacist-led, multidisciplinary transitional care clinic for heart failure (HF) patients showed good results at the Louis Stokes Cleveland VAMC in Cleveland. The report, published in Progress in Cardiovascular Diseases, noted that transitions of… Read More

How Effective are Implantable Cardioverter Defibrillators in Heart Failure?

MINNEAPOLIS – While improvement in left ventricular ejection fraction (EF) to greater than 35% occurs in many patients with reduced EF at baseline, it is not clear whether implantable cardioverter defibrillator (ICD) therapy improves survival for these patients. A study… Read More