The standard treatment for advanced prostate cancer (PC) is androgen deprivation therapy (ADT), usually delivered via a luteinizing hormone-releasing hormone (LHRH) agonist.
Surgery Is Better Treatment for Primary Aldosteronism
Even though primary aldosteronism (PA) is one of the most common causes of secondary hypertension, the comparative outcomes of targeted treatment often are unclear.
Consensus Documents Answers Some Questions on Carotid Stenosis
Many national/international guidelines provide recommendations on management of patients with asymptomatic (AsxCS) and symptomatic (SxCS) carotid stenosis. Several questions remain unanswered, however, according to a new report.
SMART2 CABG Risk Score Performs Well in Racially Diverse VA Cohort
A new study tested the potential of the Secondary Manifestations of Arterial Disease (SMART2) risk score for use in patients undergoing coronary artery bypass grafting (CABG).
Cardiac Mortality for Women Veterans Has Not Improved Over Two Decades,
Women veterans have shown a lack of improvement in cardiac mortality compared to civilian women over nearly two decades, suggesting a need for clinical interventions to improve cardiovascular care, according to a recent study.
VHA Venous Thromboembolism Rates Low After Cancer Surgery
The rates of venous thromboembolism (VTE) diagnosis are low after major cancer surgery among veterans treated at the VHA, according to a recent study
Genetic Risk Factors Lead to Potential Therapeutic Targets for Heart Failure
Heart failure affects nearly 6.2 million adults in the United States and disproportionately impacts veterans. The long-term prognosis of heart failure is poor, with a five-year mortality rate of 50%, raising the demand for new therapeutic opportunities.
Statin, Ezetimibe Therapy Combo Shows Promise for Reducing CVD Risk
Combining two different medications used to lower high cholesterol levels, optimized statin therapy and ezetimibe, appears to be associated with reducing cardiovascular risk in U.S. military veterans with coronary artery disease, according to a new study.
Flexible Prevention Bundle Appears to Reduce Some Surgical Site Infections
Surgical site infections (SSIs) are associated with significant morbidity and mortality, prolonged length of hospital stay and readmission.
Statins Affect Coronary Artery Calcium Score Used to Determine CVD Risk
A retrospective study involving more than 1,000 U.S. veterans has called into question the use of a coronary artery calcium score (CACS) to assess risk of atherosclerosis.
Disparities in Heart Failure Persist Despite MHS’s Universal Care Access
Heart failure affects an estimated 6.2 million adults in the United States and is associated with disability, diminished quality of life and a 5-year mortality of 50%.
Historical Practice of Redlining Is Linked to Adverse Cardiovascular Events
The historical practice of redlining, where neighborhoods were graded based on racial and ethnic compositions, has left a lasting impact on the health of communities across the United States.
Anti-VEGF Injections Can Cause Adverse Events in Veterans With Diabetes
Diabetes patients who are treated with anti-vascular endothelial growth factor (VEGF) injections, the primary treatment for diabetic retinopathy, have a higher likelihood of experiencing adverse events, such as acute myocardial infarction, cardiovascular disease or kidney disease, according to a recent study.
Cardiorespiratory Fitness Linked to Lower Abnormal Glucose Risk
Cardiorespiratory fitness (CRF) can be a good predictor of chronic disease. The problem is the difficulty and impracticability of routinely measuring that in primary care settings.
Cardiac Autonomic Neuropathy Linked to Stroke in T2D
What is the association between cardiac autonomic neuropathy (CAN) with incident stroke among diabetes mellitus patients?
Most Servicemembers Hospitalized With Exertional Rhabdomyolysis Have Heat Illness
Most hospitalizations in military servicemembers for exertional rhabdomyolysis, a syndrome of muscle breakdown following exercise, are associated with heat illness and present with lower creatine kinase levels than cases without associated heat illness, according to a recent study.
Stimulant Use Could Be a Key Factor in Heart Failure Development
Chronic heart failure affects an estimated 5% of veterans in the VA Health System, and annual mortality in heart failure patients is 15%
Demographics of Hypertrophic Cardiomyopathy Patients Appear to Be Changing
The typical hypertrophic cardiomyopathy patient appears to have changed somewhat, according to a new study, which pointed out that “clinicians are encountering a phenotype of hypertrophic cardiomyopathy evolving from the disease recognized several years ago.”
Survey: Post-9/11 Veterans More Likely to Exercise, Eat Right Than Civilians
BOSTON — Recent U.S. veterans reported similar or better outcomes than nonveterans when it comes to their health, vocational, financial and social well-being. That is in contrast to some earlier cohorts who had served in the military and lagged behind civilians in some domains.
SMASH2 Scoring System Better Predicts Atrial Fibrillation
CHICAGO — Atrial fibrillation-associated morbidity and mortality are on the increase, and a new study pointed out the critical need for improved surveillance and prevention strategies to reduce the condition which can lead to strokes. The report in The Journal...
Acute Heart Failure Patients Benefitted from Use of SGLT2 Inhibitors
KANSAS CITY, MO – While sodium-glucose cotransporter 2 inhibitors (SGLT2), initially used to treat type 2 diabetes, have been shown to improve health status in chronic heart failure, their effect in acute heart failure has not been as clear, according to a new study....
Causes of Hypertrophic Cardiomyopathy Extend Beyond Genetic Factors
BOSTON — For three decades, hypertrophic cardiomyopathy has basically been considered to be a genetic disease. The cause was believed to be variants in individual genes encoding cardiac sarcomere proteins. But that is changing, however, according to a review published...
VA Researchers Identify Key Factor in ACCORD’s Increased Mortality
Optimal diabetes management requires striking a careful balance. Over time, high blood glucose levels impair cardiovascular function, leading to delayed wound healing, heart disease and elevated risk of stroke.
Is Heart Rate Variation an Accurate Biomarker for PTSD?
Could heart rate variability be an indicator of when a form of transcranial magnetic stimulation would be effective in treating post-traumatic stress disorder?
Pandemic Worsened Outcomes of Out-of-Hospital Cardiac Arrest
Outcomes of out-of-hospital cardiac arrest appears to have worsened, not only nationally but also at the state level, according to a new study focusing on Texas.
HCM Management Strategies Lower Morbidity, Mortality Among Patients
New treatment guidelines endorsed highly effective hypertrophic cardiomyopathy management strategies, saying those have altered clinical course and substantially lowered mortality and morbidity rates.
Guidelines Call for Multimodal Imaging to Accurately Diagnose HCM
Multimodal imaging is crucial for the diagnosis and care of patients with hypertrophic cardiomyopathy (HCM), according to new guidelines from the American Society of Echocardiography.
Demographics of Hypertrophic Cardiomyopathy Patients Appear to Be Changing
The typical hypertrophic cardiomyopathy patient appears to have changed somewhat, according to a new study, which points out that “clinicians are encountering a phenotype of hypertrophic cardiomyopathy evolving from the disease recognized several years ago.”
In-Hospital Weight Loss Signals Improved Clinical Outcomes in HF Patients
Nearly all patients hospitalized for acute heart failure are acutely congested due to fluid retention and have gained weight by the time of their admission.
VA’s Prescribing of Direct-Acting Oral Anticoagulants Often Guideline Discordant
Since they were first approved by the Food and Drug Administration in 2010, direct-acting oral anticoagulants (DOACs) have become the most commonly-prescribed anticoagulants for nonvalvular atrial fibrillation (NVAF) due to their predictable pharmacokinetics, few drug-drug interactions and low monitoring requirements.