Recent Oncology Studies

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Vitamin D Supplementation in Veterans with Early-Stage Prostate Cancer

Objective: Vitamin D promotes the differentiation of prostate cancer cells, maintains the differentiated phenotype of prostate epithelial cells, and can induce prostate cancer cell death, raising the possibility that vitamin D deficiency over time promotes the progression of subclinical prostate cancer to clinical disease. This clinical study aims to measure the efficacy of vitamin D3 (4000IU/day) supplementation in veterans diagnosed with low-risk, early-stage prostate cancer who elect to have their disease monitored.

Sponsor: VA

Contact: Sebastiano Gattoni-Celli, MD (843) 876-5103 Sebastiano.Gattoni.-Celli@va.gov

Status: Currently recruiting

ID #: NCT00953225

Respiratory-Swallow Training in Veterans with Oropharyngeal Cancer

Objective: This research is designed to test a novel swallowing therapy that includes the coordination of breathing with swallowing. The study will train medically- and surgically-treated, chronically dysphagic veterans with histories of oropharyngeal cancer in a novel therapy that involves both swallowing and respiratory systems. If the therapy is found to be effective, the long-term goal of the project is to extend the study to a multi-site, clinical trial and test the longstanding effect of this treatment compared to other swallowing therapies on swallowing function, QOL and cost.

Sponsor: VA

Contact: Julie A Blair, MA (843) 792-7162 blairju@musc.edu

Status: Not yet open

ID#: NCT01032928

Care Partners: Web-based Support for Caregivers of Veterans Undergoing Chemotherapy

Objective: Given the growing strain on VA resulting from increasing caseloads of cancer patients, interventions are needed that assist patients in managing illness, improving quality of life, and avoiding acute episodes that result in urgent care and increased mortality. Previous studies have found that cancer patients undergoing chemotherapy can effectively manage their own symptoms when monitored using automated telephone calls. Such technology, however, may challenge veterans who lack social support and/or independence. This study’s goal is to develop and test a technology that not only monitors patients automatically by telephone, but also gives them self management advice and engages a friend or family member to serve as a Care Partner willing to play a limited role in identifying patient symptoms and psychosocial needs.This technology could substantially improve the quality of life of veterans and their families during the stresses of chemotherapy without substantially increasing the cost of care.

Sponsor: VA

Contact: Jenny S Chen, MPH BA (734) 845-3539 Jenny.Chen2@va.gov

Status: Currently recruiting

ID#: NCT00983892

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