Recent Oncology Studies

by U.S. Medicine

April 12, 2011

Vitamin D Supplementation in Veterans with Early-Stage Prostate Cancer

Objective: Vitamin D promotes the differentiation of prostate cancer cells, maintains the differentiated phenotype of prostate epithelial cells, and can induce prostate cancer cell death, raising the possibility that vitamin D deficiency over time promotes the progression of subclinical prostate cancer to clinical disease. This clinical study aims to measure the efficacy of vitamin D3 (4000IU/day) supplementation in veterans diagnosed with low-risk, early-stage prostate cancer who elect to have their disease monitored.

Sponsor: VA

Contact: Sebastiano Gattoni-Celli, MD (843) 876-5103 [email protected]

Status: Currently recruiting

ID #: NCT00953225

Respiratory-Swallow Training in Veterans with Oropharyngeal Cancer

Objective: This research is designed to test a novel swallowing therapy that includes the coordination of breathing with swallowing. The study will train medically- and surgically-treated, chronically dysphagic veterans with histories of oropharyngeal cancer in a novel therapy that involves both swallowing and respiratory systems. If the therapy is found to be effective, the long-term goal of the project is to extend the study to a multi-site, clinical trial and test the longstanding effect of this treatment compared to other swallowing therapies on swallowing function, QOL and cost.

Sponsor: VA

Contact: Julie A Blair, MA (843) 792-7162 [email protected]

Status: Not yet open

ID#: NCT01032928

Care Partners: Web-based Support for Caregivers of Veterans Undergoing Chemotherapy

Objective: Given the growing strain on VA resulting from increasing caseloads of cancer patients, interventions are needed that assist patients in managing illness, improving quality of life, and avoiding acute episodes that result in urgent care and increased mortality. Previous studies have found that cancer patients undergoing chemotherapy can effectively manage their own symptoms when monitored using automated telephone calls. Such technology, however, may challenge veterans who lack social support and/or independence. This study’s goal is to develop and test a technology that not only monitors patients automatically by telephone, but also gives them self management advice and engages a friend or family member to serve as a Care Partner willing to play a limited role in identifying patient symptoms and psychosocial needs.This technology could substantially improve the quality of life of veterans and their families during the stresses of chemotherapy without substantially increasing the cost of care.

Sponsor: VA

Contact: Jenny S Chen, MPH BA (734) 845-3539 [email protected]

Status: Currently recruiting

ID#: NCT00983892

back to April articles

Related Articles

Colonoscopy Linked to Lower CRC Mortality in Veterans

Colonoscopy is heavily promoted in the VA healthcare system, and a new study sought to document its effect on colorectal cancer (CRC) mortality rates.

Adjuvant Chemotherapy Improves Survival in Rectal Cancer

The standard of care for locoregionally advanced rectal cancer (LARC) in the United States usually involves adjuvant chemotherapy (AC) following chemoradiation (CRT) and total mesorectal excision (TME).

U.S. Medicine Recommends

More From research


First-Ever Study Focuses on How Well VHA Cares for TIA Patients

INDIANAPOLIS — While many healthcare systems measure the quality of their stroke care, looking at performance early in the vascular disease process can help avoid acute events altogether.


Link Between Pain, Brain Disruption in Gulf War Veterans

SILVER SPRING, MD — New cases of acute and chronic hepatitis C (HCV) have dropped sharply among U.S. servicemembers since 2008, bucking the nationwide trend. For the general population, the national Centers for Disease Control... View Article


VA Patients Lack Testing to Optimize CLL Treatment

SALT LAKE CITY — The presence of deletion 17p (del17), determined by chromosome analysis and/or fluorescence in situ hybridization (FISH), is a strong negative prognostic marker in chronic lymphocytic leukemia (CLL), according to a report in the Journal of Clinical Oncology.1


Early Relapse After AHCT Bad Sign in Multiple Myeloma

SILVER SPRING, MD — New cases of acute and chronic hepatitis C (HCV) have dropped sharply among U.S. servicemembers since 2008, bucking the nationwide trend. For the general population, the national Centers for Disease Control... View Article


Laparoscopic, Robotic Surgeries Equivalent for Pancreatic Cancer

Pancreatic cancer patients increasingly are receiving minimally invasive pancreaticoduodenectomy (MIPD).

Facebook Comment

Subscribe to U.S. Medicine Print Magazine

U.S. Medicine is mailed free each month to physicians, pharmacists, nurse practitioners, physician assistants and administrators working for Veterans Affairs, Department of Defense and U.S. Public Health Service.

Subscribe Now

Receive Our Email Newsletter

Stay informed about federal medical news, clinical updates and reports on government topics for the federal healthcare professional.

Sign Up