A new study identified a strong minimum effective dose/duration type relationship with statin use in veterans with prostate cancer receiving androgen deprivation therapy (ADT).
Male Breast Cancer Higher in Veteran Prostate Cancer Survivors
Male breast cancer incidence is rare, but veteran status is found to be associated with increased risk, and a higher prevalence has been identified for male veteran prostate cancer survivors.
MRI Findings Can Help Stage Prostate Cancer
MRI findings should be considered in prostate cancer staging, according to a new study led by Duke University and the Durham, NC, VA Healthcare System.
Pandemic Data: SCLC Survival Outcomes for Carboplatin Comparable to Cisplatin
Based on a consensus of clinical guidelines, cisplatin is the preferred platinum agent in the first-line treatment for small cell lung cancer (SCLC), especially limited-stage disease (LS-SCLC).
MRI Instead of Biopsy in Prostate Cancer Under Active Surveillance Appears to Result in Underdiagnosis
For about three decades, active surveillance (AS) has been the preferred management for favorable-risk prostate cancer (PC) and has traditionally included confirmatory biopsy to address any under sampling at diagnosis.
Veterans With Chronic HCV Had Increased Pancreatic Cancer, Developed It at Younger Ages
Chronic infection with the hepatitis C virus (HCV) appears to be a potentially modifiable risk factor for pancreatic cancer, according to a new study of 6.3 million U.S. veterans.
Pandemic Data: SCLC Survival Outcomes for Carboplatin Comparable to Cisplatin
Based on a consensus of clinical guidelines, cisplatin is the preferred platinum agent in the first-line treatment for small cell lung cancer (SCLC), especially limited-stage disease (LS-SCLC).
High-Risk Medications Linked to Frailty and Mortality in Veterans With Cancer
Careful medication review might be just as critical as cancer treatment itself for older adults. A large study of nearly 400,000 veterans found that certain medications commonly prescribed to this population are associated with higher risks of frailty, hospitalization and death.
What Is Link Between Merkel Cell Polyomavirus, Lung Carcinogenesis?
Even though tobacco smoking is predominantly associated with lung cancer (about 85%), another 15-25% of lung cancers occur in nonsmokers.
Tackling a Killer: Optimizing Outcomes in mHCC Through Sequencing
Despite significant progress in treatment and an expanding armamentarium of therapies, liver cancer remains the third-leading cause of cancer-related death worldwide.
Pandemic Data: SCLC Survival Outcomes for Carboplatin Comparable to Cisplatin
AMSTERDAM, the NETHERLANDS – Based on a consensus of clinical guidelines, cisplatin is the preferred platinum agent in the first-line treatment for small cell lung cancer (SCLC), especially limited-stage disease (LS-SCLC). During the COVID-19 pandemic, however,...
What Is Link Between Merkel Cell Polyomavirus, Lung Carcinogensis?
NANCHANG, CHINA – Even though tobacco smoking is predominantly associated with lung cancer (about 85%), another 15-25% of lung cancers occur in non-smokers. “This suggests that other biological cofactors, such as chronic infection and inflammation, are responsible for...
Tarlatamab Had Acceptable Safety Profile, Unprecedented OS in ES-SCLC Trial
SEATTLE -- Tarlatamab, a delta-like ligand 3 (DLL3)-directed bispecific T-cell engager immunotherapy, in combination with anti-PD-L1, demonstrated an acceptable safety profile, with long-term tolerability and “unprecedented” overall survival in small cell lung cancer,...
Albuminuria More Than eGFR Linked to Kidney Cancer
While studies have previously examined the association of chronic kidney disease (CKD) with cancer risk, results have been conflicting.
MHS Colon Cancer Surgical Outcomes Didn’t Differ by Race, Ethnicity
While access to care is known to be a contributor to racial-ethnic differences in treatment receipt and survival of colon cancer in the United States, is that also the case with colon cancer surgery?
The Critical Role of Nurse Navigators in Cancer Care for Women Veterans
A powerful health care advocate specializing in oncology, retired Maj. Gen. Marianne Mathewson-Chapman, PhD., brought both her military leadership and her personal experience as a breast cancer patient to the forefront when she addressed the Association of VA Hematology/Oncology (AVAHO) annual meeting last month in Phoenix.
Agent Orange, Genetics Independently Increase Lymphoid Malignant Neoplasms Risk
Agent Orange (AO) exposure and polygenic risk can be a double whammy when it comes the increased hazard of developing mature lymphoid malignant neoplasms, according to a new study.
Former VA Undersecretary for Health Calls for Adopt Bold Aims in Uncertain Times
Kenneth W. Kizer, MD, MPH, DCM, former VA undersecretary for health, urged clinicians and administrators to embrace uncertainty as an opportunity for courageous change.
Predicting Outcomes for Lung Cancer With Radiology/Pathology Integration
Lung cancer is the leading cause of cancer-related deaths globally and includes non-small cell lung cancer (NSCLC) (85% of cases) and small cell lung cancer (SCLC) (13–15% of cases).
New Digital Measure Sheds Light on Missed Opportunities in Cancer Diagnosis
Missed and delayed cancer diagnoses can lead to devastating outcomes. A new study has taken a major step toward quantifying and addressing this issue by developing a digital quality measure to track advanced-stage cancer diagnoses—a potential signal of preventable diagnostic delays.
Insulin Resistance Surrogates Linked to Greater Small Cell Lung Cancer Risk
Insulin resistance (IR) has shown correlation with increased cancer risk, but few studies have explored the relationship between IR and small cell lung cancer (SCLC), according to a new Chinese study.
Black Patients With Non-Hodgkin Lymphoma Fare Better With MHS Care
Poorer survival of Black patients with non-Hodgkin lymphoma (NHL) compared to white ones might be related to healthcare access issues in the general population, according to a new study.
New Findings About B-Cell Lymphomas, Novel Inhibitory Molecules
B-cell lymphomas, including Burkitt lymphoma (BL), diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL), evade CD4+ T-cell immunity through novel HLA class II-associated immunosuppressive mechanisms, according to a new study.
Tackling a Killer: New Therapies at the VA vs. Rising Rates of Hepatocellular Carcinoma
Incidence rates for hepatocellular carcinoma (HCC), which accounts for up to 85% of all liver cancers, have tripled since 1980, making it the fastest-growing malignancy by incidence in the U.S.
AI-Based Radiomic Features Help Predict Benefit, Outcomes in Advanced SCLC
With small cell lung cancer (SCLC), which is aggressive with poor survival outcomes, the majority of patients develop resistance to chemotherapy. Yet, no predictive biomarkers currently guide therapy, according to new research.
Assessing Germline POT1 Variants in a Pan-Cancer Cohort
An increased risk of several cancers have been identified in the presence of germline likely pathogenic and pathogenic variants (LPV/PVs) in POT1.
Photodynamic Therapy for Nonmelanoma Skin Cancers
The majority of cancer diagnoses in the United States each year are for skin cancer, including melanoma and nonmelanoma variants. Increasingly, those are the focus of research on treatment and prevention, according to a new study.
More Low-Value Skin Procedures With VA-Purchased Care
In an effort to improve care, in 2014, the VA implemented the Veterans Choice Program, which allowed enrollees to receive care outside VA facilities if they met eligibility requirements tied to wait times, travel and availability of services.
Predicting Outcomes for Lung Cancer with Radiology/Pathology Integration
Lung cancer is the leading cause of cancer-related deaths globally and includes non-small cell lung cancer (NSCLC) (85% of cases) and small cell lung cancer (SCLC) (13–15% of cases).
Insulin Resistance Surrogates Linked to Greater Small Cell Lung Cancer Risk
Insulin resistance (IR) has shown correlation with increased cancer risk, but few studies have explored the relationship between IR and small cell lung cancer (SCLC), according to a new Chinese study.