Million Veterans Database Used in Large-Scale Analysis for Cardiometabolic Traits

Noting that studies linking mitochondrial DNA (mtDNA) with complex traits are often limited by small sample sizes or focused on specific phenotypes in clinically selected cohorts, researchers recently reported data from more than 600,000 participants in the Million Veteran Program (MVP) to perform a multiancestry analysis of mitochondrial DNA (mtDNA) variation and cardiometabolic phenotypes across European (EUR), African (AFR), Admixed American (AMR) and East Asian (EAS) populations.

ECG-Based Devices Should Be Used to Evaluate Heart Rate Variability in Adults

In adults, pulse rate variability (PRV) and heart rate variability (HRV) aren’t interchangeable, and electrocardiography (ECG)-based devices should be used when HRV is clinically relevant and autonomic function needs to be evaluated, according to a study that addressed misinformation on wearable smart devices purchased by consumers to monitor their health.

Making Prostate Cancer Imaging More Guideline Concordant

Inappropriate imaging to stage low-risk prostate cancer is considered low-value care. A new VA study sought to determine the effectiveness of a theory-based intervention, Prostate Cancer Imaging Stewardship (PCIS), to promote guideline-concordant imaging.