Clinical Topics Home

VA More Likely To Treat Geriatric Veterans with Older AEDs

DURHAM, NC – Despite the availability of newer therapies, phenytoin remains the most prescribed antiepileptic drug (AED) within the VHA, according to a recent study. Researchers from the Southeast Epilepsy Centers of Excellence at the Durham, NC, VAMC and Duke… Read More

Army Infantry Troops Most Likely to Suffer Amputation

SAN ANTONIO ‑ Infantry troops in the U.S. Army were the most likely to suffer an amputation, according to a recent retrospective study looking at injury rates and likelihood of returning to duty. Researchers from Brooke Army Medical Center in… Read More

Understanding Brain Compensation Aids Amputee Rehabilitation

COLUMBIA, MO — University of Missouri researchers have determined how amputees compensate when losing a dominant hand, which could lead to better rehabilitation techniques for those suffering from amputation or stroke. The study was funded by the DoD.1 “Half of… Read More

FDA OK’s Marketing for Novel Prosthetic Arm

MANCHESTER, NH —The Food and Drug Administration (FDA) recently allowed marketing of the first prosthetic arm that can perform multiple, simultaneous powered movements controlled by electrical signals from electromyogram (EMG) electrodes. In the DEKA Arm System, EMG electrodes detect electrical… Read More

Cyramza Receives Fast-Track Approval for Advanced Stomach Cancer

INDIANAPOLIS – A new therapy has received fast-track approval for treatment of advanced stomach cancer. The Food and Drug Administration has approved Cyramza (ramucirumab) to treat patients with gastroesophageal junction adenocarcinoma. Cyramza, marketed by Eli Lilly of Indianapolis, is an… Read More

FDA Adds Warning to Corticosteroid Injection Labels

WASHINGTON – Corticosteroid injections given to treat neck and back pain, as well as radiating pain in the arms and legs, can have rare but serious adverse effects, according to the Food and Drug Administration (FDA). Noting that those side… Read More

Mindfulness Intervention Shown to Lower Opioid Misuse

SALT LAKE CITY – Active-duty servicemembers with chronic pain will be among the next groups tested with a new mindfulness-focused treatment to lower opioid misuse. The new intervention, called Mindfulness-Oriented Recovery Enhancement (MORE) is designed to train patients to respond… Read More

Periosteal Stimulation Therapy Shows Promise in Knee Pain

PITTSBURGH – Patients with painful knee osteoarthritis who received electrical stimulation of the periosteum facilitated by acupuncture needles showed modest improvement in pain, according to a study at the Veterans Administration Pittsburgh Healthcare System (VAPHS). Background in the article, published… Read More

Are Knee Injections by Rural Providers Cost-Effective?

SALT LAKE CITY – If enough patients are treated, training rural providers to perform knee injections for patients with osteoarthritis can be cost-effective, according to a new study funded by the VHA. Using the common threshold of $50,000 per quality-adjusted life… Read More

Approval of Topamax for Migraines Extended to Adolescents

TITUSVILLE, NJ — Food and Drug Administration approval of Topamax (topiramate) for migraine headaches prophylaxis has been extended to adolescents ages 12 to 17. It was the first FDA approval of a drug for migraine prevention in this age group.… Read More

FDA: Use Doripenem Cautiously in Ventilator-Associated Pneumonia

WASHINGTON — Label changes on Doribax (doripenem), an antibacterial drug used to treat ventilator-associated pneumonia, have been approved by the Food and Drug Administration. The FDA said the drug carries an increased risk of death and lower clinical cure rates… Read More

Prostate Cancer Recurrence Risk Rises 50% with Elevated Glucose Levels

Prostate Cancer Recurrence Risk Rises 50% with Elevated Glucose Levels

By Annette M. Boyle SEATTLE — Obesity is clearly associated with poor outcomes in patients with prostate cancer, according to past research, but the reason why has remained elusive. Now a new study suggests the real culprit might be hyperglycemia,… Read More

Group Appointments Improved Dyslipidemia in Diabetic Vets

DURHAM, NC — How effective are group medical appointments for improving dyslipidemia in veterans with uncontrolled diabetes and hypertension? A recent study led by researchers from the Center for Health Services Research in Primary Care at the Durham, NC, VAMC… Read More

Internet Tool Uses Patient Feedback to Improve Army Pain Management

Internet Tool Uses Patient Feedback to Improve Army Pain Management

By Sandra Basu WASHINGTON — A new Internet tool is a powerful weapon to combat pain, and the DoD is now launching it in a pilot location. The Pain Assessment Screening Tool and Outcomes Registry (PASTOR) recently was rolled out… Read More

Dalfampridine ER Improves Walking in Veterans with MS

PORTLAND, OR — In a recent study, Portland VAMC researchers found that, in short-term trials, dalfampridine extended release (ER) improves walking in veterans with multiple sclerosis (MS). In the study, which was published recently in Multiple Sclerosis Journal, the authors… Read More

Minority Partners Might Need More Support in Breast Cancer Decisions

MINNEAPOLIS — Nurses should pay attention to making sure that racial and ethnic minority partners should receive decision support to make sure they are sufficiently involved in decision making about breast cancer treatment, according to a new study led by… Read More

VA, Army Clinicians Rapidly Increase Prescribing of Novel Anticoagulants

VA, Army Clinicians Rapidly Increase Prescribing of Novel Anticoagulants

WASHINGTON — Use of novel anticoagulants has risen sharply both at the VA and in the Army in the last three years, freeing more atrial fibrillation patients from food restrictions and regular checks for coagulation time, as required when using warfarin.

Female Veterans Develop CVD Risk Factors at Younger Ages

Female Veterans Develop CVD Risk Factors at Younger Ages

By Annette M. Boyle BOSTON — During the past 15 years, female veterans have developed risk factors for cardiovascular disease (CVD) at ever-younger ages, challenging many providers’ concept of the population at risk for heart disease. “Historically, the focus in… Read More

VA Study: Vitamin E 'Significantly' Slows Alzheimer's Disease Functional Decline

VA Study: Vitamin E ‘Significantly’ Slows Alzheimer’s Disease Functional Decline

By Brenda L. Mooney MINNEAPOLIS — Could a vitamin found on drugstore shelves be effective in slowing cognitive decline for patients with Alzheimer’s disease? New VA research found that a daily dose of 2,000 IUs of vitamin E slowed functional… Read More