Strict LDL-C Lowering Linked to Diabetes Progression

While some guidelines recommend statin use to achieve low-density lipoprotein cholesterol (LDL-C) goal under 70 mg/dL for primary prevention of atherosclerotic cardiovascular disease (ASCVD) in patients at higher risk, others recommend against a target LDL-C level.

Weight Loss Similar in Older/Younger Veterans on Semaglutide

Concerns have been raised about GLP-1 receptor agonists causing unintended weight loss in older adults. A new VA study has put that worry to rest, finding no significant difference in weight loss with semaglutide use among veterans 65 or older compared to those who are younger. The authors concluded that age does not appear to be a “robust predictor” of semaglutide’s effect on weight.

Recent VA Review Calls for More Research on Ketogenic Diet Benefits

A recent review noted that ketogenic diets, which generally are very low in carbohydrate and very high in fat, have traditionally been employed to treat epileptic disorders, although they have been touted as a therapy for Type 2 diabetes and a range of other health conditions—neurodegenerative diseases, cancer, obesity, heart failure and nonalcoholic fatty liver disease (NAFLD).