OTTAWA, ONTARIO — Continuing concerns are being raised about the gastrointestinal safety of sodium polystyrene sulfonate, which is commonly prescribed for the treatment of hyperkalemia.
GAINESVILLE, FL — When people want to describe themselves as uncoordinated, they might say they have trouble walking and chewing gum at the same time. However, the act of walking—one of the most basic human skills—is not nearly as simple as that phrase makes it sound.
SALT LAKE CITY — A massive VA study revealed that 99% of veterans have at least one genetic mutation known to affect response to specific drugs, including some commonly prescribed antidepressants, anticoagulants, antivirals, oncology medications and statins. That raises the question of who should be tested for which variants and when, which has stirred lively debate within the VA.
SAN DIEGO — The region of the brain that processes fear, anxiety, aggression and similar emotions is larger in veterans and active-duty service members with combat-related post-traumatic stress disorder and mild traumatic brain injury than those with brain injuries only.
NASHVILLE, TN — Processes leading to impairment in schizophrenia and psychotic bipolar disorder might be more similar than previously assumed, according to a new study.
INDIANAPOLIS — Meticulously following clinical guidelines in VA patients who suffered transient ischemic attack or nonsevere ischemic stroke reduced by nearly one-third their risk of death within a year, according to a new study.
MINNEAPOLIS — Incidental pulmonary nodules are commonly found on routine chest imaging, but not enough is known about smoking behaviors among patients with IPNs or characteristics of patient-clinician communication that may contribute to these behaviors.
SAN ANTONIO — Significant airborne hazards were reported during military conflicts in southwest Asia, including geologic dusts, burn pit emissions, chemical exposures, and increased rates of smoking.
WASHINGTON — A VA panel this summer opted not to add the new depression medication esketamine, Spravato, to the department’s formulary in the usual way. This came despite strong support from President Donald Trump and an effort by VA officials to fast-track the drug for approved use at VA facilities.
HOUSTON—Veterans who have experienced acute coronary syndrome within the past year face a substantial risk of a repeat event. Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors significantly reduce that risk, but determining who would benefit most and when they should be initiated has been challenging.
BIRMINGHAM, AL — For the first time, new guidelines have recommended the use of tumor necrosis factor inhibitor biologics as initial therapy for psoriatic arthritis.
WASHINGTON—Researchers and policy makers estimated that 300,000 to 400,000 people in the U.S. had multiple sclerosis in 2010, but new data indicates that number grossly undercounted the number of people affected by the neurological disease.
BALTIMORE—A University of Maryland research team has discovered a biomarker that can determine whether a patients has multiple sclerosis or is relapsing, thanks to VA funding.
ST. LOUIS—Use of metformin for Type 2 diabetes significantly reduces the risk of dementia among African American male veterans older than 50, according to a large observational cohort study.
DURHAM, NC — Diabetes mellitus among older men has been associated with increased bone mineral density but paradoxically increased fracture risk, according to a study in the Journal of Bone and Mineral Research.1
ATLANTA—Which diabetes patients are most likely to have decompensated diabetes, defined as diabetic ketoacidosis and hyperosmolar hyperglycemic state?
PHILADELPHIA—Is esketamine a revolutionary treatment for depression or just another moderately effective adjunctive medication with some potentially serious risks? The VA’s Medical Advisory Panel leaned toward the latter position when it decided in June to approve the use of esketamine on a nonformulary basis for individuals who have previously failed at least two trials of other antidepressants.
SAN ANTONIO— Col. Andrew Cap, the division chief of Acute Combat Casualty Research at the Army Institute of Surgical Research, admits that he’s the last person you want to ask for advice on how to plan out a career in medical research.