New York—Antiretroviral therapy transformed infection with human immunodeficiency virus (HIV) from a death sentence to a chronic condition, along the way changing virtually everything about the disease, including its association with cancer. For years, specific...
Acute Kidney Injury Risk With Stem Cell Transplant
CHARLOTTESVILLE, VA – Hematopoietic stem cell transplantation can be a life-saving therapy for many patients with cancer, as well as patients with some nonmalignant hematologic disorders, such as aplastic anemia, sickle cell disease, and certain congenital immune...
Is Radiation Therapy Linked to Second Cancer Diagnoses?
STANFORD, CA – How likely is a second cancer diagnosis after primary cancer treatment with 3-dimensional conformal radiotherapy (3DCRT), intensity-modulated radiotherapy (IMRT), or proton beam radiotherapy (PBRT) for lymphoma and other cancers? Researchers from...
Circulating Stromal Cells Could Serve as Solid Tumor Biomarkers
A type of circulating stromal cell, CAMLs arise as part of an innate immune response, which could make them useful for predicting the presence of cancer. That would be particularly useful as the cells can be isolated from peripheral blood, making a test non-invasive.
How Uterine Cancer Manifests Differently in Black, White Women
Black women are more likely to die of uterine cancer than white women, even though the incidence rate is the same between the two groups.
Timely Care Not Received by Many Rural Veterans with Colorectal Cancer
For many rural patients, receiving timely, quality cancer care remains difficult. Challenges include transportation hurdles, financial constraints, a lack of providers, and minimal access to clinical trials. As a result, while cancer incidence rates are lower in rural areas, cancer mortality rates are higher.
VA Rapidly Adopted Novel Agents for Chronic Lymphocytic Leukemia
In 2015, the American Society of Clinical Oncologists (ASCO) named the transformation of chronic lymphocytic leukemia (CLL) the Cancer Advance of the Year.
More Screening Urged to Stem Increase in Colorectal Cancer in Younger Patients
Rates of colorectal cancer have been rising in younger patients since the mid-1980s, even as rates have fallen in individuals over age 50, according to the American Cancer Society.
Immunotherapy Increases Overall Survival in Veterans with NSCLC
Real world results often differ markedly from those seen in clinical trials. In the very real world setting of the VA, does immunotherapy really provide greater benefit than chemotherapy for patients with lung cancer?
Value Calculations Conflict in Genomic Profiling of Tumors
Increased personalization of cancer therapy has transformed oncology over the past decade as a growing number of targeted therapies have entered the market.
Effective EPOCH-R Treatment for Older Patients With Aggressive Lymphomas
Over the last few years, two combinations have dueled for primacy in treatment of lymphomas: DA-EPOCH-R (dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab) and R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone).
Early Progression Linked to Worse Outcomes in Metastatic Renal Cell Carcinoma
Among veterans, renal cell carcinoma (RCC) accounts for 3% of all diagnosed malignancies or approximately 2,250 new diagnoses each year.
Guideline-Concordant Skeletal Survey Might Overestimate Multiple Myeloma
The National Comprehensive Cancer Network (NCCN) Guidelines continue to recommend conducting a skeletal survey or whole-body radiography as the first step in identifying osteolytic bone lesions and distinguishing between smoldering multiple myeloma (SMM) and multiple myeloma (MM).
Prognostic Models Fail to Reflect Racial Differences in Prostate Cancer
Every physician knows each patient is different. Prognostic models, however, tend to assume everyone’s the same. That can skew decisions in cancer care.
Veteran Survival Varies Widely with Immune Checkpoint Inhibitors
Across the VA system, immune checkpoint inhibitors (ICIs) are being prescribed for a growing number of cancer types including renal cell carcinoma, lung cancer, head and neck cancers, and melanoma.
Microneedling Skin to Protect Against Non-Melanoma Cancer
DAYTON, OH —Geriatric patients are the primary victims of nonmelanoma skin cancer, according to a new study pointing out that only 20% of them are diagnosed in patients younger than 60. Part of the reason, according to an article in Archives of Dermatological...
Older Men With Prostate Cancer Likely to Die of Other Causes
LOS ANGELES —Men with biochemical recurrence after radical prostatectomy don’t always receive enough information on competing risks of mortality to inform prognosis and guide treatment, according to a new study. Cedars-Sinai Medical Center-led researchers sought to...
Survey of VHA Use of Chemoprevention for Breast Cancer
INDIANAPOLIS—Although clinicians now have tools to reduce the risk of breast cancer, most eligible women in the United States aren’t offered either personalized screening or chemoprevention. That is despite breast cancer being the most common cancer diagnosed among...
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