Extraordinary Claims Require Extraordinary Evidence

ECREE was a concept popularized by Carl Sagan to help the public understand the key features of the scientific method. It can be difficult for people to realize that science can never prove anything; instead, scientists develop a hypothesis (an educated guess about the natural world) and design tests to determine whether empirical evidence supports or contradicts the original hypothesis. To be considered science, a hypothesis must be subject to being proven false through observation or experimentation.

MASLD Risk Differs by Sex in HIV Patients

In general, men face a higher risk for metabolic dysfunction-associated steatotic liver disease (MASLD) with clinically significant fibrosis (CSF) than premenopausal women, but does the same hold true in patients with HIV?

Physician Assistants Have Close Ties to Military and Continue to Improve Care Value in MHS, VA

Eugene A. Stead, MD, of the Duke University Medical Center in Durham, NC, is credited with assembling the first class of PAs in 1965; all were former U.S. Navy hospital corpsmen and U.S. Army combat medics who had received considerable medical training during their military service, including the Vietnam War. The curriculum was based on what he remembered about the fast-tracking of MD training during World War II.

Phase 3 trial Demonstrates 63% Reduction in Schizophrenia Relapse Risk

In an era where post-traumatic stress disorder and traumatic brain injury dominate discussions of military and veteran mental health, schizophrenia spectrum disorders can be overlooked—despite the reality that young adults beginning military service are often at the age when schizophrenia symptoms first emerge.

Five Things to Know about Augmentation for Treatment Resistant Depression

Approximately half of patients with major depressive disorder fail to achieve adequate response to initial antidepressant treatment. An inadequate response is generally defined as less than 50 percent improvement in depression severity after six to eight weeks of treatment at therapeutic doses. Even partial responders, those who experience some benefit but continue to have significant symptoms, may benefit from treatment optimization or augmentation.