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Sotorasib Results Promising; Targets NSCLC Mutation Linked to Heavy Smoking

by U.S. Medicine | Jun 7, 2023

HOUSTON—While declines have been noted in recent years, U.S. veterans use tobacco at considerably higher rates than those who have never served in the military. In recent decades that rate has been as high as 30%. The high smoking rate has increased the incidence of...

Epidemiology of Lung Carcinoids Differ Slightly Within VA Healthcare

by U.S. Medicine | Jun 7, 2023

ALBANY, NY—How does the epidemiology of lung cancer differ in the VHA compared to the general population? That was the question raised by a recent study that noted that lung carcinoids (LC) “continue to increase in prevalence and existing data shows a female...

Understanding the Drug-Drug Interactions of Erlotinib and Gefitinib

by U.S. Medicine | May 31, 2023

Two drugs used in the treatment of several cancers have poorly understood drug-drug interactions that could have significant implications for patients.

Immunotherapy Improves Outcomes for Veterans With Advanced NSCLC

by U.S. Medicine | Jun 7, 2023

DURHAM, NC—Not that long ago, chemotherapy (CT) using multi-agents was considered the standard of care for advanced non-small cell lung cancer (NSCLC) patients. More recently, with the publication of clinical trials, immunotherapy (IO) has been shown to have benefits...

Does Age, Treatment Selection Drive Differences in ALL Outcomes?

by U.S. Medicine | May 31, 2023

Acute lymphoblastic (or lymphocytic) leukemia (ALL) occurs more often in children than in adults and has much better outcomes in youngsters.

Digging Deeper into Agent Orange, Genomic Alterations and Prostate Cancer

by U.S. Medicine | May 31, 2023

The defoliant known as Agent Orange has been linked to a wide range of malignancies since the conclusion of the Vietnam War, including prostate cancer.

Surprise! Short-term ADT Might Benefit Cognition in Prostate Cancer Patients

by U.S. Medicine | May 31, 2023

In an unexpected turn of events, a team including investigators with the Naval Medical Center in Portsmouth, VA., found that adding short-term androgen deprivation therapy (STADT) to prostate bed salvage radiotherapy not only reduced progression in advanced prostate cancer but also improved patients’ mental processing speed.

Real-World Study Shows Veterans with NSCLC Benefit from Durvalumab

by U.S. Medicine | May 31, 2023

The continuing conundrum of clinical trials is how to assess their applicability to the patients actually seen in practice.

Obesity/Weight Gain Associated with MGUS Progression to Multiple Myeloma

by U.S. Medicine | May 31, 2023

Obesity ranks high in the list of risk factors for the development of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM).

Walter Reed Researchers Tackle Issues with Real-World Data on Multiple Myeloma

by U.S. Medicine | May 29, 2023

Real-world data holds the promise of enabling a better understanding of how medications work in the type of patients typically seen in clinics and hospitals.

Combination Therapy Outperforms ADT Alone in Metastatic Prostate Cancer

by U.S. Medicine | May 29, 2023

Studies have shown improved survival in patients who receive either docetaxel or androgen signaling agents (ASIs) such as abiraterone or enzalutamide in combination with androgen deprivation therapy.

VA’s Equal Access Care Mitigates Disparities in HCC Treatment, Outcomes

by U.S. Medicine | May 29, 2023

Rising rates of hepatocellular carcinoma (HCC) have focused attention on improving all aspects of the malignancy, from new methods of screening, earlier detection, more efficacious treatment, and extended survival. At the same time, the increased number of cases has made differences in access and outcomes more apparent.

Nivolumab Plus Cabozantinib Improves Health-related Quality of Life in RCC

by U.S. Medicine | May 29, 2023

At the 2023 American Society of Clinical Oncology (ASCO) annual meeting in Chicago a new analysis of data from the CheckMate 9ER trial was presented.

HER2 May Provide Therapeutic Target for Pancreatic Ductal Adenocarcinoma

by U.S. Medicine | May 29, 2023

PDAC accounts for 90% of all pancreatic cancers, which have an overall five-year survival rate of just 12%.

VA Demonstrates Success in Remote Treatment of Aggressive Cancers

by U.S. Medicine | May 29, 2023

Initially, the TeleOncology service managed oral therapies and watchful waiting and surveillance of veterans with cancer, but it has expanded to offer remote supervision for intravenous cancer treatments.

VA Study Shows Low Use of Primary Care for Reproductive Health Services

by Mary Anne Dunkin | May 18, 2023

The integration of reproductive health services into primary care practices is increasingly recognized as critical to the advancement of patient-centered care and improving reproductive outcomes.

Quality Care Reduces Breast Cancer Survival Rate Disparities Based on Race

by LaTina Emerson | May 18, 2023

Though non-Hispanic Black women are more likely to have tumors at a higher grade and later stage and be diagnosed with triple-negative breast cancer

Frailty in Older Veterans Associated With Greater Suicide Attempt Risk

by LaTina Emerson | May 18, 2023

Veterans who are 65 and older and have symptoms of frailty are at increased risk of attempting suicide, and those with lower levels of frailty were found to have greater risk of suicide death, according to a new study.

Decline in Cerebral Cortical Thickness Linked to PD Cognitive Decline

by U.S. Medicine | May 16, 2023

What effect does reduced cerebral cortical thickness have in Parkinson’s disease (PD)?

Fewer Parkinson’s Motor Issues 11 Years After Deep Brain Stimulation

by U.S. Medicine | May 16, 2023

More than a decade after deep brain stimulation (DBS), early-stage Parkinson’s disease (PD) patients appeared to have fewer motor complications than those treated only with medications, according to a new study.

Cognitive Impairment Can Affect Parkinson’s Gait Rehab

by U.S. Medicine | May 16, 2023

What is the effect of baseline cognition on gait outcomes after a treadmill training program for Parkinson’s disease (PD) patients?

Cardiorespiratory Fitness Linked to Lower Abnormal Glucose Risk

by U.S. Medicine | May 16, 2023

Cardiorespiratory fitness (CRF) can be a good predictor of chronic disease. The problem is the difficulty and impracticability of routinely measuring that in primary care settings.

Cardiac Autonomic Neuropathy Linked to Stroke in T2D

by U.S. Medicine | May 16, 2023

What is the association between cardiac autonomic neuropathy (CAN) with incident stroke among diabetes mellitus patients?

Time in Range Beneficial in Patients With Individualized A1c

by U.S. Medicine | May 16, 2023

Individualizing hemoglobin A1c treatment goals in older adults is important to balance risks in benefits, according to a new study.

Deployed Servicemembers Had Lower Cancer Risks Than Those Who Weren’t

Deployed Servicemembers Had Lower Cancer Risks Than Those Who Weren’t

by Brenda Mooney | May 16, 2023

Despite concerns about exposure to hazardous material, military personnel who deployed to Southwest Asia actually had a lower risk of dying from cancer than their colleagues who were never deployed, according to a new study.

Elevated Preoperative Glucose Level Linked to Adverse Effects in Hernia Repair

by Mary Anne Dunkin | May 12, 2023

An estimated 1 in 10 Americans and 1 in 4 veterans has diabetes, not only putting them at increased risk for problems such as heart and kidney disease, but also making them more prone to complications such as infection and bleeding following surgery.

Genetics Play a Role in Severe PTSD in Some Deployed Soldiers

by Brenda Mooney | May 12, 2023

The risk for specific soldiers to have severe post-traumatic stress disorder (PTSD) appears to far predate their deployment. In fact, some military personnel are born with it, according to a new study.

Promotion Delays Affecting Military Readiness But Senator Won’t Budge

by Stephen Spotswood | May 12, 2023

Delays in promotions directly impacts military readiness, DoD officials have said. But there isn’t much they can do about it as long as Sen. Tommy Tuberville (R-AL) is blocking the expedited promotion of more than 150 military generals and flag officers

Mental Health of Veterans Before, During and After COVID-19 Pandemic

by Mary Anne Dunkin | May 12, 2023

With work disruptions, social isolation and economic concerns, the pandemic understandably caused significant distress for many veterans.

VA Secretary McDonough: PACT Act Claims Numbers Still Too Small

VA Secretary McDonough: PACT Act Claims Numbers Still Too Small

by Stephen Spotswood | May 12, 2023

VA has had more than a half-million claims filed under the new PACT Act legislation, which expands care and benefits for former servicemembers exposed to burn pits and other toxic substances during their service.

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